What is bacopa?

Bacopa monnieri (B. monnieri), also known as brahmi, is a naturally-occurring tropical plant that produces white flowers between spring and autumn, and can thrive underwater. Due to its trailing blooms, it is often used in hanging planters and gardens. However, bacopa as an herb has also been used in traditional Ayurvedic medicine due to its nootropic properties.

Benefits of bacopa

Bacopa has been used for a variety of memory-related purposes, including reducing occurrences of Alzheimer’s disease and attention deficit-hyperactivity disorder (ADHD). Let’s explore some of the existing research below.

Alzheimer’s disease
A 2017 study found that bacopa is promising in reducing the effects of Alzheimer’s, but requires more research due to the small sample size utilized. Additionally, the Alzheimer’s Organization states that bacopa “removes Amyloid, one of the main causes of Alzheimer’s, from the brain.”

However, other researchers have reached different conclusions. A 2022 study, for example, reported that there was no difference between the impact of bacopa and that of a placebo on individuals with Alzheimer’s disease. It is likely that more research will need to be conducted to explore these varying results and monitor any long-term effects.

Improving memory
A 2008 study at the University of Oregon examined individuals aged 65 or older and found that bacopa supplements increased cognitive performance. Similarly, the Neuropsychology Laboratory at the School of Biophysical Science and Electrical Engineering in Australia conducted a study in which certain participants were given bacopa on a daily basis, and others were given a placebo. The results illustrated cognitive improvement in those who had taken bacopa. Finally, researchers in 2012 who employed a similar study reported that bacopa improved cognitive performance in 9 out of 17 memory recall tests.

Reducing stress and anxiety
Stress and anxiety have steadily increased in recent years, likely due to the effects of the COVID-19 pandemic. At the beginning of 2023, a study by CFAH revealed that more than 27% of American adults suffer from anxiety, COVID-19 caused a 25% increase in anxiety, and 94% of workers feel stressed out.

Bacopa may be useful in reducing stress and anxiety for a variety of reasons. First, it may increase neurotransmitters, which regulate emotions. It may also impact the hypothalamic-pituitary-adrenal (HPA) axis, which is directly involved in stress.

Attenion deficit-hyperactivity disorder (ADHD)
A 2014 study that explored the effects of bacopa extract on children with ADHD produced promising results. These researchers reported that symptoms for restlessness reduced in 93% of the children and self-control increased in 89%. Further, the extract was well-tolerated by the children studied.

Possible side effects of bacopa

Few research has been published on the side effects of bacopa, which is why it is important to consult a doctor to determine appropriate dosage. Similar to the side effects of other natural medications, taking bacopa may lead to:
• Diarrhea
• Nausea
• Dry mouth
• Stomach cramps
• Allergic reactions

Bacopa in our products

Turmeric Innovations, Inc. has conducted extensive research on bacopa to determine its benefits when combined with turmeric. Our product, Memory Rockets, contains a full-spectrum blend of turmeric and bacopa, intended to protect brain health by improving memory, cognitive function, and mood. For more information about our company and products, please visit our website and online store.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. product are not intended to diagnose, treat, cure, or prevent any disease.

What is Valerian?

Valerian, also known as Valerianae radix, is a perennial flowering plant and belongs to the Valerianaceae family, a group of plants typically identifiable by their pungent odors. A native of Europe and parts of Asia, valerian has been used in traditional medicine dating back to Greek and Roman times and is believed to have calming and sedative properties. Today, it is commonly found in various teas.

Valerian contains:

• Valerenic acid, which can help increase gamma-aminobutyric acid (GABA), a neurotransmitter in the brain. Studies have shown that valerenic acid may also be anti-inflammatory.

• Iridoids, which have been studied for their sedative effects.

• Isovaleric acid, which may be useful for preventing muscle contractions.

• Hesperidin, which has sleep-enhancing properties.

• Linarin, which also has sleep-enhancing properties.

Benefits of Valerian

Historically, valerian has been used to reduce insomnia and anxiety. However, it has also been studied for its effects on various menstrual-related conditions.

Reducing insomnia
Researchers in 2015 published a systematic review and meta-analysis about the relationship between valerian and various sleep disorders. These researchers concluded that valerian may improve quality of sleep and that research should be prioritized, given the rise of insomnia in adults across the globe. However, more research would be needed with larger sample sizes to determine long-term effects.

Indeed, many researchers have since employed more rigorous studies. For instance, a 2021 study explore the effects of valerian extract on sleep quality in patients who had recently undergone coronary artery bypass graft surgery. They reported that it may be a useful sleeping aid. Similarly, a 2022 study investigating valerian’s effects on sleep in various surgical patients presented promising results: adults 65 years or older, women recovering from surgery, and people saying in hospitals for longer periods showed evidence of improved sleep.

Finally, a 2020 study looking at valerian’s impacts on general sleeping issues found that it may be helpful in combination with other treatments. The researchers noticed interesting patterns, stating that valerian may be “more useful in treating insomnia associated with particular psychiatric conditions such as anxiety.”

Reducing anxiety
Anxiety and insomnia are frequently linked. Insomnia can worsen anxiety symptoms, and anxiety can cause insomnia. For this reason, it is not surprising that valerian has also been studied for its effects on anxiety.

Currently, research on this topic is limited, but various studies indicate valerian’s potential. A 2020 study illustrated that valerian improved anxiety, but its low solubility was a hurdle for participants. Additionally, a 2021 study employed a randomized, double-blind and placebo-controlled study on 39 patients with kidney failure, reporting a reduction in anxiety and depression in those who took valerian extract.

Hot flashes due to menopause
A 2013 study noted that, “hot flash is among the most common complaints of menopausal women, affecting their career, social activities and quality of life.” Consequently, these researchers sought to investigate whether valerian could reduce hot flashes in affected women. The study involved 68 women, all of whom were given 255 mg valerian capsules thrice a day for eight weeks. The results illustrated that these women experienced reductions in the severity and frequency of their hot flashes.

Possible side effects of valerian
Although valerian is generally considered safe, it may cause the following side effects:

• Headaches

• Dizziness

• Stomach aches

• Drowsiness

• Vivid dreams

• Heart palpitations

• Dry mouth

It is important to consult a healthcare professional to determine appropriate dosage, especially for those with underlying medical conditions and those taking additional medications.

Valerian Extract in our Products

At Turmeric Innovations, we use Valerian extract in some of our products, including our TurAsleep™ lozenge. TurAsleep® also contains jatamansi extract, nutmeg extract, and turmeric to support restful sleep.

For more information about our company and products, please visit our website and online store.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. products are not intended to diagnose, treat, cure, or prevent any disease.

Sleep is an essential component for maintaining overall health and wellbeing. During sleep, the brain performs necessary recovery processes which boost physical and mental functioning for the next day and over the long term. Consequently, lack of sleep can lead to negative outcomes, such as stress, impaired memory, and daytime drowsiness.

According to a 2023 report by CFAH, approximately 50 to 70 million Americans suffer from a sleep disorder. Additionally, 30 – 40% of adults in the United States have reported symptoms of insomnia. These statistics illustrate a pressing need for treatments that can restore restful sleep.

Taking melatonin may be a natural way to improve sleep, as well as other issues such as seasonal depression. Keep reading to learn more about the benefits of melatonin, its possible side effects, and how we use melatonin in our turmeric-based products.

What is melatonin?

Melatonin is a natural hormone produced by the pineal gland in the brain. It helps synchronize the body’s circadian rhythm, or 24-hour clock which responds to environmental cues such as light.

Melatonin can also be produced synthetically in a lab and taken as a dietary supplement. In the United States and Australia, melatonin is available over the counter. However, it requires a prescription in Europe; in some countries, such as the U.K., it is available only for people over 55 who have sleep disorders.

Benefits of melatonin

Better sleep
Myriad studies have shown that taking melatonin before bed can improve sleep. For instance, a 2016 study examined the effects of melatonin on 50 cancer patients with insomnia and found that taking a melatonin supplement two hours before bed helped many of them fall asleep. Some participants also reported improvements in overall sleep quality. Similarly, a report in 2013 analyzed 19 studies involving melatonin use in both children and adults, and noted similar patterns of improved sleep.

As these studied acknowledge, reports of improved sleep are varied and subjective. Melatonin may help some people fall asleep faster, whereas it may only minimally increase sleep time for others. It is also possible that melatonin will cause some to wake up feeling more refreshed than usual. Other studies have found that melatonin is no better than a placebo, but that placebos can certainly help reduce sleeping issues.

Reducing symptoms of seasonal affective disorder (SAD)
Seasonal affective disorder (SAD) is a type of depression related to seasonal cycles and is thought to affect approximately 5 – 10% of Americans each year. According to a 2015 study, “People with SAD may also have difficulty with overproduction of melatonin. [. . .] As winter days become darker, melatonin production increases and, in response, those with SAD feel sleepy and lethargic. Although melatonin likely plays a role in impacting the symptoms of SAD, it cannot by itself account for these phenomena.” In other words, it is common for people who experience SAD in the winter to overproduce melatonin.

However, some people experience SAD in the summer, which may lead to sleeping issues. In this case, taking melatonin may be beneficial.

Increase growth hormone levels
The human growth hormone, or HGH, is a natural hormone that stimulates cell growth, reproduction, and regeneration. HGH has been linked to increased muscle mass and reduction of body fat. Several studies have demonstrated that melatonin may stimulate HGH, particularly in men. One study explored eight men aged 22-35 and found that 0.5mg and 5mg of melatonin both increased HGH levels. A study in 1999 with 32 men made similar conclusions.

Eye health
According to a 2013 study, melatonin is “believed to be involved in the modulation of many important retinal functions; it can modulate the electroretinogram (ERG), and administration of exogenous melatonin increases light-induced photoreceptor degeneration. Melatonin may also have protective effects on retinal pigment epithelial cells, photoreceptors and ganglion cells.” These properties have sparked research on the relationship between melatonin and a wide variety of ocular functions.

One study explored the impact of 3mg of melatonin on age-related macular degeneration (AMD). After 6 months of treatment, the researchers concluded that melatonin seemed to delay macular degeneration and that there were no side effects in the patients. A 2013 study determined that melatonin supplementation is an effective treatment for AMD.

Possible side effects of melatonin

Melatonin is generally considered safe to use in the short term, and its side effects are typically mild. However, although melatonin does not cause chemical dependency, those consuming it for longer periods have a higher likelihood of becoming dependent on it for restful sleep. Melatonin may also become less effective after repeated use.

The most common side effects of melatonin are:

• Headache

• Dizziness

• The “hangover effect”

• Daytime drowsiness

• Nausea

• Hypothermia

Other side effects may include vivid dreams, stomach cramps, irritability, mood swings, and palpitations.

It is important to consult a doctor before consuming melatonin to determine appropriate dosage and potential risks associated with other medications. Older adults in particular should carefully consider the side effects listed above — one study found that adults prone to balance issues may be at higher risk when taking melatonin, and that people with dementia may become more withdrawn.

Melatonin in our products

TuraSleep, one of our newest lozenges, combines melatonin with full spectrum turmeric, Jatamansi extract, nutmeg extract, and Valeriana extract. This product can be used as an aid for sleeping soundly and feeling more alert upon waking up.

For more information about our available products, please visit our online store.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. product are not intended to diagnose, treat, cure, or prevent any disease.

During this period, many researchers have explored the use of herbs and natural supplements—turmeric included—for patients with varying symptoms. Turmeric’s anti-viral, anti-bacterial, and anti-inflammatory properties, among other benefits, have thus far shown promising results in combatting COVID-19.

Much of this research is in its early stages, but nonetheless illustrates turmeric’s diverse uses and potential to transform modern medicine. We will provide an overview of this research below.

Recent research illustrates promising results 

It is well known that COVID-19 can cause anosmia (loss of sense of smell) and ageusia (loss of sense of taste). These symptoms can be devastating, but turmeric may be able to help. A 2021 study specifically explored turmeric’s effects on anosmia and ageusia in two patients. Each COVID-19 patient took one 1000 mg dose of a turmeric supplement, which also included Boswellia serrata and black pepper extract. Both subjects reported improvement of their taste and smell abilities within minutes to hours. The researchers acknowledge the small sample size and subjectivity when determining restoration of taste and smell; however, this study could serve as an important starting point for future research.

Other researchers explored turmeric’s effects against COVID-19 in vitro. They reference other studies exploring turmeric and HIV, Hepatitis C, and Influenza A, noting that it may be effective against COVID-19 for similar reasons. They also presented favorable results.

A more recent study in 2022 included hospitalized COVID-19 patients with varying degrees of symptoms. They found that curcumin—turmeric’s active component—helped fight inflammation and that using it in combination with traditional treatments led to relief of common COVID-19 symptoms, shorter hospitalization time, and even fewer deaths.

Why does turmeric appear to work? According to a 2020 study, curcumin can help block the main protease (Mpro) of COVID-19, which is how the virus replicates. A 2021 study revealed that curcumin may hinder COVID-19’s spike protein, thus blocking the virus from entering cells.

The results of the above studies indicate the need for future research and illustrate the potential benefits of naturopathic treatments in addition to traditional medicine that has already been proven as effective against COVID-19.

For more information about Turmeric Innovations’ products, please visit our website. Our products are available for purchase here.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. product are not intended to diagnose, treat, cure, or prevent any disease.

Benefits of Boswellia

Boswellic acid, which comes from the tree’s resin, is known to be anti-inflammatory, leading to treatment for osteoarthritis, rheumatoid arthritis, asthma, and inflammatory bowel disease (IBD). Let’s explore each of these use cases in more detail below.

Reducing inflammation
In 2020, researchers published a report about Boswellia’s effectiveness on osteoarthritis, which details the results of seven trials involving 545 patients. They found that Boswellia may be a successful treatment if taken for at least four weeks. In the same year, a research study revealed that Boswellia extracts benefitted rats with osteoarthritis by reducing pain and protecting cartilage.

Similarly, researchers have explored whether Boswellia is effective in treating rheumatoid arthritis. For instance, a 2019 study looked at an animal model of rheumatoid arthritis and found a decrease in ankle swelling and arthritic index.

Boswellia and asthma
In 2023, approximately 262 million people suffer from asthma, 25 million of whom live in the United States. The good news is that Boswellia has been linked to improvements in asthma for decades. A 1998 research study found that 70% of participants with bronchial asthma experienced fewer attacks after consuming 300 milligrams of B. serrata gum for six weeks. Additionally, a 2015 study reported a decrease in number of inhalations in asthma patients who consumed Boswellia.

Boswellia and inflammatory bowel disease (IBD)
Types of inflammatory bowel disease include ulcerative colitis and Crohn’s disease, both of which have been studied in relation to Boswellia treatment.

For example, a 2015 study revealed that Boswellia helps preserve the “intestinal epithelial barrier from oxidative and inflammatory damage.” In 2001, researchers determined that Boswellia serrata extract appears to be a better treatment than mesalazine for Crohn’s disease. A different 2015 study presented similar results: Boswellia serrata gum resin is as effective as mesalazine for Crohn’s disease treatment.

Possible side effects of Boswellia

Research has shown that the side effects of Boswellia are minimal, but those who consume it regularly may experience nausea, diarrhea, constipation, acid reflux, or skin rashes.

On rare occasions, researchers have reported the following side effects:

• Allergic reactions: A 2016 research report indicated that this is more likely with topical Boswellia.

• Miscarriages: Boswellia may trigger increased blood flow to the uterus, leading to pregnancy complications and changes in menstrual flow.

For those interested in taking Boswellia and similar products, it is important to consult a doctor, especially for those with existing health conditions and pregnant women.

Boswellia in our products

Interestingly, a 2018 comparative and placebo-controlled study explored the efficacy of an extract with Boswellic acid and Curamin on osteoarthritis. The researchers obtained favorable results, reporting that “twelve-week use of curcumin complex or its combination with Boswellic acid reduces pain-related symptoms in patients with OA. Curcumin in combination with Boswellic acid is more effective.” Another 2018 research study found that curcuminoid and Boswellia formations could enhance knee osteoarthritis treatment.

At Turmeric Innovations, Inc. we sought to create a product with a similar combination. Our lozenge, TuraFlex™, includes Boswellia root and Turmeric with the goal of reducing inflammation, and improving strength and flexibility. For more information about our company and products, please visit our website and online store.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. product are not intended to diagnose, treat, cure, or prevent any disease.

What is the difference between holy basil and traditional basil?

Across the globe, there are between 50 and 150 different types of basil plants. Although all types of basil belong to the mint family, there are key differences between holy basil and traditional basil.

Traditional basil is mostly used for culinary purposes due to its sweeter taste. It is not known to have therapeutic effects, though it does contain several nutrients. Holy basil has more of a “bite” due to its spicy and peppery flavor, and is not commonly used in cuisine.

Benefits of holy basil and basil oil

Holy basil has dense phytonutrients which contribute to its medicinal and therapeutic benefits. Below are some of the most interesting use cases.

Fighting bacteria and infections

Thus far, published research has indicated that holy basil may be effective in fighting a wide variety of bacteria and infections—both in humans and in animals. A 2016 research study demonstrated holy basil’s “antimicrobial activity against S. aureus (including MRSA) and E. coli” and suggested that it appears to be very effective against skin infections in particular. An invitro study from the same year found that holy basil showed antimicrobial activity against Actinobacillus actinomycetemcomitans, which is often associated with periodontitis.

During the COVID-19 pandemic, researchers from Rush University Medical Center conducted a study on holy basil, stating that it would be necessary to find another means of reducing COVID-19 after the majority of the population had been vaccinated. They found that a specific compound in Tulsi reduced lung inflammation and decreased fevers. They also studied a mouse model of COVID-19, learning that holy basil helped restore normal heart function. However, it is likely that more research will be needed to acquire consistent results.

Holy basil and diabetes

Researchers in 2017 reviewed relevant literature about the effects of Tulsi on type II diabetes and found that, although the studies were small and short-term, most reported a reduction in blood sugar. More recently in 2021, researchers conducted randomized trials on type II diabetes patients, during which they monitored blood sugar levels before and after holy basil leaves powder consumption. They determined a positive impact.

Holy basil and cancer

One of the more interesting use cases of holy basil is for cancer treatment. Research suggests that holy basil can inhibit COX-2, an enzyme that triggers inflammation, pain, and sometimes cancerous cells. Although most research is in its early stages and hasn’t been conducted on humans, the results are promising. For instance, a 2007 study involving a mouse model of skin cancer found that holy basil, when combined with an alcoholic extract, helped reduce tumor production. In 2013, researchers found that holy basil reduced lung cancer cell growth in mice. There are numerous similar studies on breast cancer, prostate cancer, liver cancer, stomach cancer, and oral cancer.

Possible side effects of holy basil and basil oil

Given that holy basil is found in many teas and over-the-counter capsules and extracts, it is generally considered safe. A 2017 report titled, “The Clinical Efficacy and Safety of Tulsi in Humans: A Systematic Review of the Literature” found that there were no known side effects.

However, a 2020 research report suggested that, when taken in excessive amounts, holy basil may lead to:

• Effects on fetal development

• Changes in menstrual cycles

• Reduction of reproductive gland functions (especially in males)

• Low blood sugar levels

• Increased heart rates

• Nausea

• Diarrhea

• Liver damage

Holy basil in our products

Holy basil’s myriad use cases are ideal for creating a variety of different oils, supplements, and other products. At Turmeric Innovations, Inc., we chose to explore holy basil’s effects on pain mangement. Our product, PainAways™, includes Himalayan basil and turmeric for a holistic way to fight aches and pains. For more information about our company and products, please visit our website and online store.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. product are not intended to diagnose, treat, cure, or prevent any disease.

In recent years, researchers have continued to explore turmeric’s benefits and contributed to its developing interest worldwide. Many of these researchers have come to similar conclusions—that turmeric may be a useful dietary supplement for boosting the immune system, reducing inflammation, improving oral health, and more. However, one obstacle is that its effects have been minimized due to its low solubility and low permeability.

At Turmeric Innovations, Inc., we developed a solution. By employing a patented extraction process of turmeric’s primary component, curcumin, we are able to create products that are water-soluble and absorbable, thus improving efficacy. Clinical tests demonstrate that turmeric-based lozenges dissolved in the mouth provide 85% absorption, bypassing the digestive process and going directly into the circulatory system.

Keep reading to learn more about the following topics:

• What is turmeric?

• Potential benefits of turmeric

• Potential side effects of turmeric

• The future of turmeric and our products

What is turmeric?

Turmeric, or Curcuma longa, is a naturally-occurring plant most commonly found in Southeast Asia and the Tropics. Turmeric is a perennial in the ginger family; its stem grows underground and it produces above-ground flowers. Curcumin, which is the stem’s main component, gives turmeric its vibrant yellow-orange color.

Potential benefits of turmeric
Turmeric’s anti-oxidant and anti-inflammatory properties have inspired diverse research studies around the world. Although it is often difficult to study due to its low solubility and low permeability, many researchers have reported similar positive results.

Blood sugar control
According to the CDC’s 2022 National Diabetes Statistics Report, 37.3 million Americans (11.3% of the population) have diabetes. This number has significantly increased during the past decade. Type 1 diabetes occurs when the body destroys insulin-producing cells, negatively affecting blood sugar regulation.

A 2013 study suggested that curcumin can “favorably affect most of the leading aspects of diabetes, including insulin resistance, hyperglycemia, hyperlipidemia, and islet apoptosis and necrosis,” as well as prevent other diabetes-related complications. Similarly, a 2021 study reported that curcumin is a safe, low-cost alternative to certain diabetes treatments, but its effective dose is unknown.

Boosting the immune system
A 2007 study sought to explore turmeric’s effects on the immune system and found numerous interesting findings. First, a low does of curcumin can enhance antibody responses. Second, it seems to be able to modulate white blood cells, which play an active role in fighting infections and other harmful pathogens. Researchers who conducted similar experiments in 2022 recognized curcumin’s immune system benefits, but cited its low solubility as an obstacle for wide clinical use.

Reducing pain and inflammation
Due to the increase of health disorders caused by inflammation, more people are turning to anti-inflammatory diet supplements. Turmeric may be one reliable option. For example, in a 2021 study focusing on individuals with knee osteoarthritis, participants experienced pain reduction and improved joint function. A 2016 study that focused on joint arthritis presented a compelling case for turmeric as a dietary supplement for existing joint treatment.

Improving oral health
Turmeric has the potential to support oral health in numerous ways. Despite its vibrant color, one of its most popular applications is teeth whitening. Oftentimes, turmeric is combined with coconut oil and baking soda to make a whitening paste, which may also be useful for reducing gum inflammation and bad breath. On the contrary, a 2021 in-vitro study determined that turmeric was ineffective against oral bacteria, though the authors note that they utilized a limited sample size and it is possible that turmeric mouth washes might work better when combined with other substances.

Boosting cognition
In 2023, it is estimated that more than 6.7 million Americans over the age of 65 suffer from Alzheimer’s Disease. Additionally, Alzheimer’s-related deaths more than doubled between 2000 and 2019. These statistics suggest a pressing need for researchers to explore methods for boosting cognition.

Thus far, researchers have demonstrated that turmeric may be effective in reducing or preventing cognitive decline. For instance, a 2018 study determined through preclinical studies that turmeric “decreases both systemic and neuroinflammation as well as improves redox state.” Another study published in 2019 found that curcumin presents promising strategies for boosting cognition, but there is insufficient evidence for its use as dementia treatment. It is likely that more research will be necessary for consistent conclusions.

Potential side effects of turmeric
The Food and Drug Administration (FDA) has stated that curcuminoids are “generally regarded as safe.” Additionally, clinical trials have generally produced positive results of turmeric uses. Regardless, it is possible that turmeric may result in side effects if taken with other drugs or supplements, or in large doses, including:

• Headaches

• Nausea

• Rashes

• Diarrhea

The future of turmeric and our products

As turmeric becomes more widely used and researchers continue exploring its benefits, it is likely that new uses and opportunities will emerge. At Turmeric Innovations, Inc., we intend to be a part of this journey and will continue to innovate to provide absorbable and delicious products. For more information about our products, please visit our website. Our products are available for purchase here.

The above statements have not been evaluated by the Food and Drug Administration. Turmeric Innovations, Inc. product are not intended to diagnose, treat, cure, or prevent any disease.